Mecklenburg Heart Specialists
Vascular Institute & Vein Center

 Cardiovascular Research and Innovation Program

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Mecklenburg Heart Specialists , Vascular Institute and Vein Center participates in several research studies and clinical trials.

 

Current Studies & Trials — Open for Enrollment

Below are active clinical research studies currently enrolling patients at Mecklenburg Heart Specialists. Participation in these trials helps advance cardiovascular and vascular medicine while offering eligible patients access to innovative therapies.

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● FINALITY-HF – Finerenone in patients with heart failure intolerant or ineligible for steroidal MRAs (2025)

 

● CONFIRMATION-HF – Finerenone plus SGLT2i in hospitalized heart failure patients (2025)

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● V-INTERVENTION – Inclisiran vs placebo for prevention of cardiovascular and limb events post PCI or peripheral intervention (2025)

 

● SOS-AMI – Selatogrel Outcome Study in suspected acute myocardial infarction (2025)

 

● LILAC – Phase 3 study of abelacimab in high-risk atrial fibrillation patients unsuitable for oral anticoagulation (2022)

 

Completed  Studies & Trials 

 

● NODE-303 – Etripamil nasal spray for paroxysmal supraventricular tachycardia (2019)

 

● PROMINENT – Triglyceride reduction and cardiovascular outcomes in diabetes (2019)

 

● ANTHEM-HF STUDY – Autonomic regulation therapy in heart failure with reduced ejection fraction (2019)

 

● DIAMOND STUDY – Study for the management of hyperkalemia ( high blood potassium ) in adults taking certain medications for heart failure.. (2019)

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● VITALITY-HFpEF – Vericiguat in HFpEF patients (2018)

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